Third was organized in 1850 with "the love of Christ constraining and God's glory as the end in view." The church moved in 1885 to our present location which before urban sprawl was the busiest street corner in the city . Our building at Grand and Washington, in the heart of Grand Center, stands as an icon in the crowded ways of life.

Long known for its leadership in Baptist missions worldwide, the church was grounded in beliefs that made it a kingdom anchor on its home turf. During the Civil War, when St. Louis was at the center of turmoil in a border state, the pulpit at Third spoke strongly for civil rights and set the course for the church's continuing inclusive stance on matters of race and gender.